| 单词 |
Madaus Brand of Anistreplase |
| 释义 |
Madaus Brand of Anistreplase | 《英文msh词典》Madaus Brand of Anistreplase | | [入口词] Madaus Brand of Anistreplase | | [主题词] Anistreplase | | [药动学] Plasminogen Activators | | [英文释义] An acylated inactive complex of streptokinase and human lysine-plasminogen. After injection,the acyl group is slowly hydrolyzed,producing an activator that converts plasminogen to plasmin,thereby initiating fibrinolysis. Its half-life is about 90 minutes compared to 5 minutes for TPA; (TISSUE PLASMINOGEN ACTIVATOR); 16 minutes for URINARY PLASMINOGEN ACTIVATOR and 23 minutes for STREPTOKINASE. If treatment is initiated within 3 hours of onset of symptoms for acute myocardial infarction,the drug preserves myocardial tissue and left ventricular function and increases coronary artery patency. Bleeding complications are similar to other thrombolytic agents. |
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