| 释义 |
Protein 1,IGF-Binding | 《英文msh词典》Protein 1,IGF-Binding | | [入口词] Protein 1,IGF-Binding | | [主题词] Insulin-Like Growth-Factor Binding Protein 1 | | [英文释义] One of the six homologous proteins that specifically bind insulin-like growth factors (SOMATOMEDINS) and modulate their mitogenic and metabolic actions. The function of this protein is not completely defined. However,several studies demonstrate that it inhibits IGF binding to cell surface receptors and thereby inhibits IGF-mediated mitogenic and cell metabolic actions. (Proc Soc Exp Biol Med 1993;204(1):4-29) |
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