| 单词 |
Serotonin 1D Receptors |
| 释义 |
Serotonin 1D Receptors | 《英文msh词典》Serotonin 1D Receptors | | [入口词] Serotonin 1D Receptors | | [主题词] Receptor,Serotonin,5-HT1D | | [英文释义] A serotonin receptor subtype that is localized to the CAUDATE NUCLEUS; PUTAMEN; the NUCLEUS ACCUMBENS; the HIPPOCAMPUS,and the RAPHE NUCLEI. It plays a role as a terminal autoreceptor that regulates the rate of SEROTONIN release from nerve endings. This serotonin receptor subtype is closely related to and has similar drug binding properties as the 5-HT1B RECEPTOR,but is expressed at low levels. It is particularly sensitive to the agonist SUMATRIPTAN and may be involved in mediating the drug's antimigrane effect. |
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