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单词 Thrombin Receptor Activating Peptides
释义

Thrombin Receptor Activating Peptides

《英文msh词典》Thrombin Receptor Activating Peptides
[入口词] Thrombin Receptor Activating Peptides
[主题词] Receptors,Thrombin
[英文释义] A family of proteinase-activated receptors that are specific for THROMBIN. They are found primarily on PLATELETS and on ENDOTHELIAL CELLS. Activation of thrombin receptors occurs through the proteolytic action of THROMBIN,which cleaves the N-terminal peptide from the receptor to reveal a new N-terminal peptide that is a cryptic ligand for the receptor. The receptors signal through HETEROTRIMERIC GTP-BINDING PROTEINS. Small synthetic peptides that contain the unmasked N-terminal peptide sequence can also activate the receptor in the absence of proteolytic activity.
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更新时间：2026/10/14 22:08:09