| 释义 |
c-trk,Proto-Oncogene Products | 《英文msh词典》c-trk,Proto-Oncogene Products | | [入口词] c-trk,Proto-Oncogene Products | | [主题词] Receptor,trkA | | [英文释义] A protein-tyrosine kinase receptor that is specific for NERVE GROWTH FACTOR; NEUROTROPHIN 3; neurotrophin 4,neurotrophin 5. It plays a crucial role in pain sensation and thermoregulation in humans. Gene mutations that cause loss of receptor function are associated with congenital insensitivity to pain with anhidrosis,while gene rearrangements that activate the protein-tyrosine kinase function are associated with tumorigenesis. |
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